Granulocytic Expression of CD11b/CD18 and Thrombotic Risk in Patients with Myeloproliferative Neoplasms

Summary Myeloproliferative neoplasms (MPN) are clonal hematological conditions characterized by excessive production of one or more cell lines in the bone marrow. The blood cells produced often hyperactive their functions, which could lead to complications disorder‘s clinical course. We aimed define role granulocytic CD11b/CD18 expression for thrombotic risk MPN patients. investigated 110 patients with a histologically confirmed diagnosis myeloproliferative disease and control group 46 healthy volunteers. In patient group, we found an average 4.59 times higher than group. highest was subgroup polycythemia vera – 71.55% patients’ neutrophils. each essential thrombocythemia, myelofibrosis, chronic myeloid leukemia, history complication had without such complications.